The Errors of the National Academy of Sciences Booklet - Harun Yahya
THE ERRORS OF THE NATIONAL
ACADEMY OF SCIENCES BOOKLET A Reply to the National Academy of Sciences
Booklet, Science and Creationism
THE NAS'S ERROR IN PORTRAYING
MOLECULAR BIOLOGY AS EVIDENCE OF EVOLUTION
Perhaps the worst of the
totally unrealistic claims in the NAS booklet appear in the chapter
"New Evidence from Molecular Biology." Once again, the NAS proves
in this chapter that it totally discounts all the research and observations
over the last 50 years, and supports the theory of evolution in the
face of the scientific facts.
The reason why living things possess similar
structures and features is that they all have one Creator: The
Almighty God.
Those scientific facts it regards as proof of the theory
of evolution in fact bear no such interpretation. The NAS and other
evolutionists accept the theory of evolution as a proven scientific
fact first, and only afterwards interpret the results of scientific
research and observation in the light of that theory. These interpretations
are then offered as evidence of evolution. As we shall be seeing in
the following pages, such procedures are examples of the circular reasoning
employed by evolutionists.
The Error that Molecular Similarities Are Evidence
for Evolution
The basic claim of this chapter is that "The unifying principle
of common descent that emerges from all the foregoing lines of evidence
is being reinforced by the discoveries of modern biochemistry and molecular
biology." (Science and Creationism, p. 17). The first example
of these proofs in the booklet is nothing other than an assumption produced
in the light of evolutionist preconceptions. It is, of course, a fact
that the code which translates the nucleotide sequences into amino-acid
sequences is the same in all living things, and that the proteins in
all living things consist of the same 20 amino acids. The NAS's error
lies in inferring from this fact the conclusion that living things descended
from a common ancestor. This inference is quite ridiculous. Evolutionists
first assume that the theory of evolution is an established fact, and
then claim that facts deduced from the theory constitute evidence in
support of the theory. However, the fact that all living things possess
the same features and functions can also be interpreted as proof of
the existence of a common design. There is one Creator Who creates and
designs all living things, for which reason it is only to be expected
that they all should consist of the same basic features and structures.
Myoglobin is not the Evolutionary Ancestor of
Hemoglobin
Above: A myoglobin molecule
Right: A hemoglobin molecule
In the chapter "New Evidence from Molecular Biology,"
the examples of the molecules hemoglobin and myoglobin are cited,
and it is suggested that there is an evolutionary relationship between
the two. The claim takes this form in the NAS book: "each chain [that
make up hemoglobin] has a heme [group] exactly like that of myoglobin,
and each of the four chains in the hemoglobin molecule is folded exactly
like myoglobin. It was immediately obvious in 1959 that the two molecules
are very closely related."
It is perfectly natural that vehicles
designed for similar purposes should have similar features.
For example, every conveyance has a rudder or steering wheel.
This principle also applies to proteins with a "common design."
It is true that the molecules hemoglobin and myoglobin
possess similar features. What is not true is the suggestion by the
NAS and other evolutionists that this similarity constitutes proof
that hemoglobin evolved from myoglobin. These claims rest on no scientific
foundation and are simply the work of evolutionist prejudice. Let
us consider the reasons for this:
It first needs to be made clear that myoglobin and hemoglobin are two
molecules with similar functions; hemoglobin carries oxygen in the blood,
myoglobin takes the oxygen from hemoglobin and stores it in the tissues,
providing oxygen to the working muscles. It is therefore very natural
that two protein molecules with similar functions should have been designed
to have similar properties. To draw an analogy, all transport vehicles
possess similar features; they almost all have an engine, a steering
wheel, wheels, and special sections to hold cargo or people. It is evident
that, because of these similarities, every one of these vehicles was
designed for a specific purpose and possesses common features in line
with that purpose. Hemoglobin and myoglobin are molecules designed for
a similar purpose, for which reason they have similar features.
When we look at the NAS claim in a little more detail, its impossible
nature can be seen more clearly. According to the claim, myoglobin gradually
evolved as a result of mutations, differences formed in the amino-acid
sequence, and thus the hemoglobin molecule emerged. However, we know
that both myoglobin and hemoglobin possess exceedingly complex structures.
If either of these molecules is subjected to random factors like mutation,
the molecule's function will be corrupted, as we saw in the chapter
on mutations, and it will become useless. The disease known as sickle-cell
anemia is one example of this. Therefore, to expect a mutation which
randomly changes a protein's amino-acid sequence to turn that protein
into a more complex one with more features is to believe in the impossible.
In order to prove the evolutionist claims, every transitional stage
between myoglobin and hemoglobin needs to be functional (and more advantageous
than the preceding stage), and that is impossible.
A food mixer and a concrete mixer were
designed for similar purposes. Despite their different appearances,
they possess similar functions and structures.
The American chemist Dr. Robert Kofahl, a critic of the
theory of evolution, makes the following comment on the impossibility
of the claim that hemoglobin evolved from myoglobin:
A good example of alleged
molecular homology is afforded by the a- and b- haemoglobin molecules
of land vertebrates, including man. These supposedly are homologous
with an ancestral myoglobin molecule similar to human myoglobin. Two
a- and two b- haemoglobin associate together to form the marvelous
human hemoglobin molecule that carries oxygen and carbon dioxide in
our blood. But myoglobin acts as single molecules to transport oxygen
in our muscles. Supposedly, the ancient original myoglobin molecules
slowly evolved along two paths until the precisely designed a- and
b- haemoglobin molecules resulted that function only when linked together
in groups of four to work in the blood in a much different way under
very different conditions from myoglobin in the muscle cells. What
we have today in modern myoglobin and haemoglobin molecules are marvels
of perfect designs for special, highly demanding tasks. Is there any
evidence that intermediate, half-evolved molecules could have served
useful functions during this imaginary evolutionary change process,
or that any creature could survive with them in its blood? There is
no such information. Modern vertebrates can tolerate very little variation
in these molecules. Thus, the supposed evolutionary history of the
allegedly homologous globin molecules is a fantasy, not science.1
The structure of a hemoglobin molecule
As Dr. Kofahl makes clear, the NAS's claims regarding
molecular homology are not science at all, but merely fantasy, like
all its other claims.
Moreover, the evolutionists' accounts fail to explain the
origin of the myoglobin protein. They say that hemoglobin evolved from
myoglobin, but how myoglobin came into existence is still a mystery
to them.
Molecular Comparisons Conflict with The So-Called
Family Tree
The so-called family trees obtained from
analyses of such molecules as hemoglobin, myoglobin, and cytochrome
c conflict both with one another and with other data.
It is suggested in Science and Creationism
that an evolutionary family tree can be drawn up by comparing the
proteins in living things, such as hemoglobin, myoglobin, or cytochrome
c, and that this tree will agree with the paleontological and anatomical
facts. This claim is set out in these terms:
[T]he differences between sequences from
different organisms could be used to construct a family tree of hemoglobin
and myoglobin variation among organisms. This tree agreed completely
with observations derived from paleontology and anatomy about the
common descent of the corresponding organisms.
Similar
family histories have been obtained from the three-dimensional structures
and amino acid sequences of other proteins, such as cytochrome c (a protein
engaged in energy transfer) and the digestive proteins trypsin and chymotrypsin.
The examination of molecular structure offers a new and extremely powerful
tool for studying evolutionary relationships. (Science and Creationism,
p.18)
It is astonishing that the NAS should make such a claim,
ignoring important research and findings in this area. In actuality,
comparisons of the molecules cited by the NAS actually represent enormous
difficulties for the theory of evolution and reveal its inconsistencies.
Before examining the contradictions and errors of the NAS and the
theory of evolution in this area, let us provide some information
about molecular comparisons.
The protein molecules on which the structures and functions
of living things depend consist of amino acids. There are 20 kinds
of amino acids in proteins. One particular sequence of amino acids
might give rise to a fat-digesting protein in the stomach, while another
chain of amino acids might cause an oxygen-binding protein molecule
to form. Generally speaking, the amino-acid sequence is the same for
the same kind of protein in the same species. However, the amino-acid
sequence can change between species. This is the case, for instance,
with the hemoglobin molecule, which allows oxygen to be carried in
the blood. The practice of comparing the differences in a particular
protein molecule between species in order to draw conclusions about
evolutionary relationships is known as "molecular homology." For instance,
the amino-acid sequences of the hemoglobin molecules in human beings,
mice, and horses can be identified and compared. According to evolutionists,
the protein sequences of species assumed to have a closer evolutionary
relationship should be closer to one another. For instance, the sequences
in the hemoglobins of human beings and horses should be closer to
each other than to those of rats. Yet, research in this field has
revealed a conflict between comparisons at the molecular level and
the claims of the theory of evolution. Following are some of the research
conclusions that have revealed this contradiction:
Comparisons carried out on the molecule cytochrome
c, cited by the NAS as evidence for evolution, resulted in disappointment
for evolutionists. These comparisons showed that the turtle was closer
to birds than to the snake, another reptile. Evolutionists had claimed
that the protein sequences of the turtle and snake, two reptiles, should
be much closer to each another. 2
The same research also revealed that chickens exhibit greater similarities
to penguins than to ducks. Man emerges as closer to kangaroos than to
apes.3
An article in the January 2002 edition of Popular Science magazine revealed
that the DNA of the "grebe," a bird that looks like a duck was found
to be resembling a flamingo.4
As a result of the comparisons of the amino-acid sequence of the hormone
LH, amphibians were shown to be closer not to reptiles, as the theory
of evolution maintains, but to mammals.5
In comparisons performed on the alpha hemoglobin protein,
it was established that the crocodile and the chicken shared at least
15% of their amino-acid sequences. Next came the viper and the chicken
(10.5%). The crocodile and the viper-which, being reptiles, should have
had the highest level of similarity-actually possessed a very low level
(5.6%). Colin Patterson said that this example had clearly undermined
the evolutionists' assumptions.6
In myoglobin comparisons, crocodiles were seen to have
a 10.5% similarity to lizards.
However, the lizard also has a 10.5% similarity to the
chicken. In other words, the reptile/reptile level of similarity is
the same as the reptile/bird level.7
In comparisons of lysosome and lactalbumin, it emerged
that man was closer to the chicken than to the other mammals tested.8
Adrian Friday and Martin Bishop from the University
of Cambridge analyzed various tetrapod protein sequences. In an astonishing
result, human beings and chickens emerged as each other's closest relatives
in almost all examples. The next closest relative was the crocodile.9
Studies on relaxins by Dr. Christian Schwabe, a biochemical
researcher from the University of South Carolina Medical Faculty, also
produced interesting results:
Against this background of high variability
between relaxins from purportedly closely related species, the relaxins
of pig and whale are all but identical. The molecules derived from
rats, guinea-pigs, man and pigs are as distant from each other (approximately
55%) as all are from the elasmobranch's relaxin. ...Insulin, however,
brings man and pig phylogenetically closer together than chimpanzee
and man. 10
In a 1996 study, analyses of 88
protein sequences placed rabbits in the same group as primates, instead
of rodents.11 A 1998 study analyzed 13 genes in 19
species of animals, as a result of which sea urchins were grouped with
chordates. Another study in 1998 analyzed 12 proteins, as a result of
which cows emerged as closer to whales than to horses.12
As a result of his studies on cytochrome c, Richard Holmquist of the
University of California revealed that the biochemical difference between
amphibians and reptiles-classes that should be closely related according
to the theory of evolution-is greater than the difference between birds
and fish, which should be much further apart according to the theory.
Indeed, the difference between amphibians and reptiles is even greater
than that between mammals and fish or between mammals and insects. The
researcher makes the following comments:
In either case, certain anomalies appear in certain vertebrates
with respect to the magnitude of these changes and their relationship
to time. Such anomalies show up on "phylogenetic trees" as apparently
negative rates of evolutionary divergence, or incorrect taxonomic
placement of an organism in the wrong family...
... However the difference
between the turtle and rattlesnake of 21 amino acid residues per 100
codons is notably larger than many differences between representatives
of widely separated classes, for example, 17 between chicken and lamprey,
or 16 between horse and dogfish, or even 15 between dog and screw
worm fly in two different phyla.13
As the numbers of such studies increases,
it becomes ever clearer that comparisons at the molecular level conflict
with the theory of evolution. Many evolutionist biologists have had
to admit this fact. For example, the French biologists Hervé Philippe
and Patrick Forterre admitted in an article in 1999 that "with more
and more sequences available, it turned out that most protein
phylogenies contradict each other as well as the rRNA tree."
14
Basic proteins for life: insulin (left)
and relaxin.
The molecular biologists James Kale, Ravi Jain, and Maria
Rivera from the University of California wrote in 1999:
…[S]cientists started analyzing a variety
of genes from different organisms and found that their relationship
to each other contradicted the evolutionary tree of life derived from
rRNA analysis alone. 15
Biologist Carl Woese of the University of Illinois, who
is renowned for his work on establishing family trees based on RNA-based
comparisons, made the following comment on the conflicting nature
of his results in an article published in the NAS's Proceedings
of the National Academy of Sciences (PNAS):
No consistent organismal phylogeny
has emerged from the many individual protein phylogenies so far produced.
Phylogenetic incongruities can be seen everywhere in the universal
tree, from its root to the major branchings within and among the various
[groups] to the makeup of the primary groupings themselves. 16
Biologist
Michael Lynch states that the results of analyses of the same genes
have been as contradictory as those on different genes:
Clarification of the
phylogenetic [i.e., evolutionary] relationships of the major animal
phyla has been an elusive problem, with analyses based on different
genes and even different analyses based on the same genes yielding
a diversity of phylogenetic trees.17
Furthermore, molecular biologist Michael Denton says
that comparisons at the molecular level conflict with the theory of
evolution:
However as more protein
sequences began to accumulate during the 1960's, it became increasingly
apparent that the molecules were not going to provide any evidence
of sequential arrangements in nature, but were rather going to reaffirm
the traditional view that the system of nature confirms fundamentally
to a highly ordered hierarchic scheme from which all direct evidence
for evolution is emphatically absent. Moreover the divisions turned
out to be more mathematically perfect than even most die-hard typologists
would have predicted. 18
According to the tree based on ribosomal
RNA, the evolutionary ancestor split into two branches, archaea
and bacteria. Later still, eukarya developed from archaea. Yet,
recently sequenced microbial genomes and comparisons with eukaryotic
genomes such as yeast conflict with this claim and represent
yet another dilemma for evolutionists.
Dr. Schwabe is a scientist who has dedicated years to
finding proof of evolution in the molecular field. He has attempted
to establish evolutionary relationships between living things by studying
proteins such as insulin and relaxin, in particular. Yet he has had
to confess several times that at no point has he been able to obtain
any evidence for evolution. In an article published in the journal
Science, he states:
Molecular evolution
is about to be accepted as a method superior to paleontology for the
discovery of evolutionary relationships. As a molecular evolutionist
I should be elated. Instead it seems disconcerting
that many exceptions exist to the orderly progression of species as
determined by molecular homologies; so many in fact that I
think the exception, the quirks, may carry the more important message.
19
Professor Donald Boulter, of Durham University's Biological
Sciences Department, announced in 1980 that the results of his comparisons
of amino-acid sequences conflicted with the assumptions of the theory
of evolution:
Initial
results obtained by using amino acid sequences of vertebrate cytochrome
c led to an outline of the phylogeny of the vertebrates which was similar
to that derived from fossil evidence. This very encouraging start was
soon to change to a less satisfactory one as the results from other proteins
were assembled. Amino acid sequence data sets of different proteins did
not always lend themselves to the same phylogenetic interpretation or
agree with the accepted phylogeny obtained mainly from fossil or morphological
characters.20
An article headed "Genome Data Shake the Tree of Life,"
written by Elizabeth Pennisi and published in the journal Science,
revealed that analyses at the molecular level had shaken the evolutionists'
so-called evolutionary tree and that the results were contradictory:
Since then, he [evolutionist
Carl Woese] and others have used rRNA comparisons to construct a "tree
of life," showing the evolutionary relationships of a wide variety
of organisms, both big and small. According to this rRNA-based tree,
billions of years ago a universal common ancestor gave rise to the
two microbial branches, the archaea and bacteria (collectively called
prokarya). Later, the archaea gave rise to the eukarya. But the newly
sequenced microbial genomes and comparisons with eukaryotic genomes
such as yeast have been throwing this neat picture into disarray,
raising doubts about the classification of all of life.21
Pennisi stated that the bacterium Aquifexaeolicus, which lives at a temperature close to boiling point
and whose DNA sequence has been unravelled, made concrete the problems
facing molecular evolutionists. Robert Feldman, a molecular geneticist
and one of the scientists involved in the study of the bacterium,
summed up his results at the Conference on Microbial Genome held at
Hilton Head, North Carolina, in February 1998: "You get different
phylogenetic placements based on what genes are used."22
The article also summarized some of the data which emerged
from the research:
The gene for a protein
called FtsY, which helps control cell division, placed Aquifex
close to the common soil microbe Bacillus subtilus, even
though the two supposedly come from different branches of the bacterial
tree. Even worse, a gene encoding an enzyme needed for the synthesis
of the amino acid tryptophan linked Aquifex with the archaea.
That wasn't the only anomaly the Diversa team found regarding the
archaea, however. Their analysis of the gene encoding the enzyme CTP
synthetase, which helps make the building blocks of DNA, spread the
archaea out among all the other organisms evaluated, suggesting that
they may not be as coherent and distinct a group as the rRNA tree
implies.23
Another scientist whose views were cited in Pennisi's
article was the Ohio State University microbiologist John Reeve. He
said:
Before, people tended to equate rRNA
trees with the [life history] tree of the organism. From the whole genomes,
you very quickly come across [genes] that don't agree with the rRNA
tree.24
SIMILARITIES DO NOT MEAN AN EVOLUTIONARY RELATIONSHIP
Evolutionists
suggest a so-called evolutionary relationship between living things
on the basis of certain genetic or morphological similarities between
them. However, research in recent years has shown that genetic and morphological
studies do not represent evidence for the claim that there is an evolutionary
relationship between living species.
Same Genes, Different Appearance:
One of the latest studies in this area was carried out
by the US National Science Foundation. The research, led by the evolutionary
biologist Blair Hedges from Penn State University, compared the genes
of aquatic birds. It emerged from this study that birds claimed to
be members of the same family actually bore no similarity to one another
at all from the genetic point of view. The study summarized its conclusions
in these terms:
The genes of aquatic birds have revealed a family tree
dramatically different from traditional relationship groupings based
on the birds' body structure.1
Molecular comparisons revealed that the
nearest relative of the flamingo is a small diving bird with
short legs designed for that purpose. This result conflicts
with the evolutionary family tree.
Until recently, evolutionists constructed phylogenetic
relationships between species by comparing physical characteristics.
Thanks to DNA analyses, however, researchers have finally realized
that that the evolutionary family trees drawn up on the basis of physical
features are invalid.
Among the surprising findings made by researchers was
that there is no physical similarity between creatures with very similar
genes:
The most startling and unexpected finding of the study
is that the closest living relative of the flamingo, with its long
legs built for wading, is not any of the other long-legged species
of wading birds but the squat grebe, with its short legs built for
diving.2
The evolutionary biologist Blair Hedges expressed his
astonishment at this surprising finding:
The two species-whose genes are more similar to each other's
than to those of any other bird-otherwise show no outward resemblance.3
Same Appearance, Different Genes:
A similar finding emerged with the discovery of a new
species of salamander in Mexico. The scientists first imagined that
they had found a specimen of a known salamander, but following DNA
analysis they concluded that they were mistaken. That was because
although the appearance of the soil dwelling salamander they had found
was identical to known salamanders, genetically it was very different.
The National Science Foundation announced the following conclusion:
The soil dwelling salamander looks identical to one living
in mountain foothills several hundred miles away. But DNA analysis
by NSF-funded zoologists at the University of California at Berkeley
shows them to be a distinct species.4
This led to an astonishing conclusion: despite being
identical to each another, the two creatures had to be classified
as different species at the genetic level. David Wake of the University
of California at Berkeley, the biologist in charge of the research,
openly stated the conclusion he had reached: They are not one another's
closest relatives.
External similarity does not therefore imply genetic
similarity. This outcome is surprising to the experts, because the
fact that two species are genetically very different certainly means
that they did not evolve from a common ancestor, and that there is
no phylogenetic relationship between them.
In the light of these evaluations, the so-called evolutionary
relationships assumed by evolutionists based on morphological or genetic
similarities have been shown to be invalid. Therefore, all the family
trees so far drawn up are without scientific foundation and rest solely
on evolutionist preconceptions.
1. Cheryl Dybas, Genes
of Aquatic Birds Reveal Surprising Evolutionary History, National Science
Foundation - News Tip, August 1, 2001 2. Cheryl Dybas, Genes of Aquatic
Birds Reveal Surprising Evolutionary History, National Science Foundation
- News Tip, August 1, 2001 3. Cheryl Dybas, Genes of Aquatic
Birds Reveal Surprising Evolutionary History, News Tip, August 1, 2001 4. Cheryl Dybas, "New" Salamanders
Turn Up from DNA Analysis, National Science Foundation - News Tip, August
1, 2001
The Cytochrome C/Hemoglobin Error
It is claimed in the NAS booklet that the family trees
obtained from comparing molecules such as cytochrome c and hemoglobin
provide proof of the theory of evolution. According to this claim,
the similarities between the amino-acid sequences of these molecules
in living things show that they evolved from one another. This claim
is totally false. The fact that there are some similarities between
molecules like cytochrome c or hemoglobin in some species is no proof
that the creatures in question evolved from one another.
First and foremost, it needs to be made clear that, as
we have just seen, comparisons performed on other molecules give very
different and conflicting results, incompatible with any evolutionist
picture.
A table listing thirty-three
comparisons between bacterial cytochrome c of Rhodospirillum
rubrum, and the cytochrome c of other living things. As can
be seen from this table, every class is definitively separated
from the other classes, and no intermediate forms can be seen
at the molecular level. All the sequences of every subclass
are equidistant from the members of the other groups. In other
words, the molecular sequences of classes that should be more
closely related according to the evolutionists' claims are not
in reality closer to one another. 26
What biochemists have found with their comparisons of
certain proteins like cytochrome c and hemoglobin is this: It is possible
to classify species into groups according to their molecular structure.
These groups are compatible with the groups produced by comparative
anatomy. However, the interesting thing in such a protein "atlas"
is that these groups or subclasses are totally isolated from one another.
No intermediate forms are to be found between groups-just as there
are no transitional forms either in the fossil record or among living
groups today. Species are always separated from one another by definitive
lines of division.
The Australian biochemist Michael Denton
draws attention to the fact that tables such as the Dayhoff Atlas
of Protein Structure and Function, which show divergence of the
cytochromes, reveal the absence of any such transitional forms in
the clearest way possible.25
Here is another noteworthy point in this connection:
According to evolutionists, the most primitive organisms-those lacking
a cell nucleus-are prokaryotes, or bacteria. Higher organisms with
a nucleus in the cell, from yeasts to human beings, are known as eukaryotes.
If all eukaryotes evolved from bacteria, as evolutionists would have
us believe, then one would expect to see a graduated divergence in
their proteins such as cytochrome c. Yet, what we actually find is
this: the cytochrome c of all the main classes-from human beings to
kangaroo, from the fruit fly to the chicken, from the sunflower to
the rattlesnake, and from the penguin to baker's yeast-all exhibit
the same degree of divergence from the cytochrome c molecules of bacteria
(varying between 65 and 69%).
Michael Denton offers the following comment:
Eucaryotic cytochromes,
from organisms as diverse as man, lamprey, fruit fly, wheat and yeast,
all exhibit a sequence divergence of between sixty four per cent and
sixty seven per cent from this particular bacterial cytochrome. Considering
the enormous variation of eucaryotic species from unicellular organisms
like yeasts to multicellular organisms such as mammals, and considering
that eucaryotic cytochromes vary among themselves by up to forty-five
per cent, this must be considered one of the most astonishing findings
of modern science.27
What is even more extraordinary is that there is no evidence
in biochemistry of the most fundamental evolutionary scheme-the transitions
from fish to amphibians, from amphibians to reptiles, and from reptiles
to mammals. The protein divergence of land vertebrates like amphibians,
reptiles, and mammals, when compared to those of fish, all appear
isolated to exactly the same degree. The gradual divergence envisaged
by evolutionary sequence is not observed.
From the point of view of their cytochrome c, horses,
rabbits, frogs, and turtles are 13% divergent from the carp. Denton
says:
At a molecular level, there is no trace
of the evolutionary transition from fish to amphibian to reptile to
mammal. So amphibia, always traditionally considered intermediate
between fish and the other terrestrial vertebrates, are in molecular
terms as far from fish as any group of reptiles or mammals.28
As we have seen, the "facts" from molecular biology that
the NAS portrays as evidence for the theory of evolution are all either
errors or else deliberate distortions by evolutionist scientists.
The Pseudogene Error
Another
of the aspects of molecular biology that the NAS represents as proof
of the theory of evolution is the sequences of DNA known as "pseudogenes,"
which are claimed to have no function. (Science and Creationism,
p. 20)
As we know, the proteins in an organism's body are produced
by means of the information coded in its genes. Pseudogenes are assumed
to play no role in the production of protein, or anything else, and
are therefore regarded as "functionless."
The concept of pseudogenes is actually
part of the "junk DNA" thesis, which maintains that there are parts
of DNA which serve no purpose. The fact is, however, that this thesis
was revealed to be totally mistaken by a series of discoveries beginning
in the second half of the 1990s. The DNA sequences that were alleged
to be "junk" were all found, one by one, to perform very important
functions in cells and the body. Findings from 1992 revealed that
the genes described as junk actually contained vital codes with information
about the general structure of the body and about the timing of when
other genes should be switched on and off. According to the Washington
Post, "Key scientists said the new discoveries
were likely to force them to abandon the term 'Junk DNA.' "29
Then again, even if there really were pseudogenes within
the cell, they would still avail the theory of evolution nothing.
The reason why evolutionists regard pseudogenes as proof
of descent from a common ancestor is that they consider them to be
errors in DNA caused by mutations. They suggest that it is impossible
for similar errors to arise in different species, for which reason
these errors must have been handed down over the generations throughout
the evolutionary process. The fact is, however, that there is a great
of evidence to disprove that claim. For example:
1.
Some gene regions are more disposed to mutation. It is therefore no
surprise that the same gene regions should have mutated in different
species, and this does not require descent from a common ancestor.
2. The evidence that pseudogenes, alleged to be functionless,
actually do serve a purpose is, as we have seen, increasing day by
day.
3. The phylogenetic trees constructed suing pseudogenes
both are internally inconsistent and also conflict with other phylogenetic
trees.
1.
The fact that some gene regions are more disposed to mutations invalidates
the evolutionists' claims about pseudogenes. It has been established
that there are "popular mutation points" in many genes and pseudogenes.30
This means that some regions in DNA sequences are more disposed than
others to undergo mutation, and these are mutations which have no
effect on the organism. It is therefore probable that these regions
in the DNA of different living things have been subjected to mutation
and that the same nucleotides have changed. It is illogical to claim
solely on the basis of these similar mutations that these living things
descended from a common ancestor.31
2. The evidence that pseudogenes, alleged to be functionless,
actually do serve a purpose is, as we have seen, increasing all the
time.
The reason why evolutionists portray pseudogenes as evidence
for the theory of evolution is that they assume them to have no function.
However, as was made clear at the beginning, many pseudogenes believed
to be functionless have actually turned out to be nothing of the sort.
Evidence of this kind is increasing all the time. Moreover, as some
scientists have stated, the fact that these DNA sequences have never
been observed to encode proteins in an experimental environment does
not mean they lack the ability to do so. Indeed, A.J. Mighell, of
the Leeds University Molecular Medicine Department, has this to say
on the subject:
In these and other examples it cannot
be stated with certainty that a gene is unequivocally either a pseudogene
or a gene. It is possible that analysis has not been performed in
the appropriate temporo-spatial conditions to detect expression.32
E.
Zuckerkandl, G. Latter, and J. Jurka criticize the way in which the
claim that pseudogenes have no function is treated as an established
fact,
DNA not known to be coding for proteins
or functional RNAs, especially pseudogenes, are now at times referred
to in publications simply as nonfunctional DNA, as
though their nonfunctionality were an established fact.33
In
fact, one of the best-known pseudogene groups, Alu, had always been
regarded as functionless and was only recently proved to serve a purpose
after all.34 It is also thought that some pseudogenes
and RNA have a mutual effect on one another.35 Some
pseudogenes, it is believed, also have a function as sources of information
for forming genetic variety.36
AN X-RAY OF THE COCCYX In the nineteenth century, evolutionists
produced lists of hundreds of "vestigial organs," which they
used as evidence for evolution. This list grew increasingly
shorter during the twentieth century, however, when it was established
that organs believed to be functionless actually had very important
uses for the body. The coccyx is one of these.
It
is thought that some parts of pseudogene sequences are copied to functional
genes and produce various forms of the functional sequence. This has
been reported several times. Examples include the immunoglobins of
mice 37 and birds 38, mouse histone
genes, 39 horse globin genes,40
and human beta globin genes.41
Some pseudogenes
have been observed to be linked to gene regulation.42
A role of this kind may include competition for regulatory proteins,
the production of signal RNA molecules and other mechanisms.43
All these examples are sufficient to undermine the claim
that there are "pseudogenes" in living things. A great deal of evidence
has now been accumulated with regard to pseudogenes, which shows that
the claim that pseudogenes are not beneficial cannot be trusted.
Molecular comparisons between human beings,
chimpanzees, and gorillas show that man and apes did not evolve
from a common ancestor. These analyses invalidate the claims
of the theory of evolution.
In the nineteenth century, evolutionists produced a list
of hundreds of supposedly atrophied organs in the human body, such
as the appendix and coccyx, which they claimed had lost their functions
during the process of evolution. Thanks to the scientific and technological
advances made during the twentieth century, however, the list of so-called
"vestigial" organs shrank enormously, and it was realized that organs
originally believed to have no function actually possess features
of great importance for life. It seems that a similar process is now
transpiring with the pseudogenes, and the so-called proofs to which
evolutionists have attached their hopes are disappearing one by one.
3. The phylogenetic trees constructed using pseudogenes
are both internally inconsistent and also conflict with other phylogenetic
trees.
On the other hand, the phylogenetic
trees which evolutionists construct using pseudogenes conflict both
internally and with other evolutionary trees. For example, a recent
article entitled "How Reliable Are Human Phylogenetic Hypotheses?,"
authored by M. Collard and Bernard Wood and published in the NAS's
own publication, PNAS, makes clear that according to the evolutionary
tree constructed on the basis of pseudogenes, human beings emerged
before chimpanzees and gorillas. However, according to the evolutionists'
own claims, the chimpanzee and gorilla emerged before man.44
Of course, inconsistencies of this
kind are not peculiar to comparisons made among the human-chimpanzee-gorilla
threesome. For instance, an attempt has been made to construct a general
primate phylogeny (evolutionary tree) by comparing beta globin molecule
data. It was observed, however, that two pieces of data were contradictory.45
In
another study, Alu sequences revealed that lemurs (a small primate
species) and hominids (man) are sibling groups.46
This conclusion, however, conflicts with data which locate the lemur
in a different place in the primate phylogeny. The presence of similar
pseudogenes in phyla which are regarded as evolutionarily far removed
from one another is something evolutionists cannot account for.47
A new example of this is the SINE sequences, a particularly surprising
discovery. These pseudogene sequences are shared among living things
far removed from each other in evolutionary terms, such as trout 48,
rodents, and inkfish.49
The contradictions seen in the phylogenetic
trees constructed using other molecules can also be seen in those
built on the basis of pseudogenes. These facts are quite sufficient
to show that pseudogenes do not represent evidence of descent from
a common ancestor.50
Some pseudogene sequences are shared by
such very different creatures as rodents and ink fish. This
is just one of the many examples demonstrating that pseudogenes
represent no evidence for evolution.
The Molecular Clock Error and Still More Circular
Reasoning
Another
phenomenon that the NAS puts forward as proof of evolution is the so-called
"molecular clock" (Science and Creationism, p. 19), which was
first suggested in the mid-1960s. This hypothesis assumed that a comparison
of genetic differences between living species regarded as being close
evolutionary relatives, together with the "divergence" periods among
living things identified from the fossil record, could be used to calculate
a definite "rate of evolution." For example, assuming that all mammals
descended from a common ancestor, as well as that the common ancestor
of the horse and the kangaroo lived some 70 million years ago, the "rate
of evolution" could be calculated by dividing the genetic difference
between the two species by 70 million years.
In
this way, the average speed of the evolutionary change in a gene or
protein became known as the "molecular clock." Evolutionists maintain
that the molecular clock reveals when living things began to diverge
from one another, thus helping to establish a time frame for such events,
as well as evolutionary relationships.
When it was first proposed, this hypothesis was greeted
by evolutionists with great enthusiasm as a major trump card to be
used against creationists. However, soon afterwards it emerged that
it clashed with the data, especially with molecular evolutionary theories
and paleontological findings.
Both the numbers and the family trees
produced by using the molecular clock are at wide variance with the
fossil record. For instance, paleontologists believe that human beings
and apes split apart from one another at least 15 million years ago.
According to the molecular clock, however, this split should have
taken place only 5 to 10 million years ago.51
In more recent periods, as a result
of analyses of mitochondrial DNA, which can only be passed down in
the female line, it was proposed that modern man was descended from
a woman who had lived in Africa as early as 200,000 years ago. Anthropologists
rejected this finding, however, because they would then have had to
discount all Homo erectus and older fossils that were dated
at more than 200,000 years.52
Norman Pace
One of the clearest indications that
the molecular clock method is unreliable was reported in an article
in Science in 1996. The article described how the biochemist Russell
Doolittle and his team had used the molecular clock method to propose
that single-cell creatures with a nucleus (eukaryotes) split off from
those without a nucleus, such as bacteria (prokaryotes), some 2 billion
years ago. However, using a different clock, the evolutionist microbiologist
Norman Pace suggested that this event took place 3 to 4 billion years
ago (even though it is generally accepted that life on Earth goes
back no further than 3.7 billion years). On the other hand, the microfossil
expert William Schopf rejected both results and claimed that the oldest
fossils of bacteria are 1.5 billion years older than the date given
by Doolittle. In the face of this claim, Doolittle expressed his doubts
as to whether these fossils were real.53 As we can
see, the use of the molecular clock produces results that not only
are internally inconsistent, but also openly conflict with the fossil
record.
In addition, the biochemists C. Schwabe
and G. W. Warr state that their analyses of relaxin (a hormone secreted
in the final days of pregnancy) are not compatible with the "evolutionary
clock model."54
The DNA analyses by the researchers L. Vawter and W.
M. Brown produced results that were totally outside evolutionists'
expectations; as a result, these researchers call for the molecular
clock hypothesis to be totally abandoned:
[The]
disparity in relative rates of mitochondrial and nuclear DNA divergence
suggests that the controls and constraints under which the mitochondrial
and nuclear genomes operate are evolving independently, and provides
evidence that is independent of fossil dating for a robust rejection
of a generalized molecular clock hypothesis of DNA evolution.55
Even evolutionist researchers thus accept that the results
obtained from the molecular clock are not trustworthy.
Another reason why the molecular clock hypothesis is
not to be trusted is that the techniques used to measure the molecular
distance between living species are not accurate. Professor James
S. Farris of the Swedish Museum of Natural History states:
It seems that the only
general conclusion one can draw is that nothing about present techniques
for analyzing molecular distance data is satisfactory . . . None of
the known measures of genetic distance seems able to provide a logically
defensible method, and it appears that some altogether different approach
will have to be adopted for analyzing electrophoretic data.56
Farris's criticisms of the techniques in question are
widely respected because he himself developed one of the most frequently
employed techniques for measuring genetic distance.
Professor Siegfried Scherer, director of the Institute
of Microbiology at the Technical University of Munich, emphasizes
the unreliability of the molecular clock in these terms:
Considering the strong
demands usually applied in experimental biology, it is hard to understand
why the [molecular clock] concept survived such a long period at all.
It can neither be used as a tool for dating phylogenetic splits nor
as reliable supportive evidence for any particular phylogenetic hypothesis.
. . . A reliable molecular clock with respect to protein sequences
seems not to exist. . . . It is concluded that the protein molecular
clock hypothesis should be rejected.57
In short, the evolutionists' molecular clock does not
work. According to Denton, the concept of the molecular clock consists
of "apologetic tautologies." Denton criticizes the theory of evolution
in these terms:
The hold of the evolutionary
paradigm is so powerful that an idea which is more like a principle
of medieval astrology than a serious twentieth-century scientific
theory has become a reality for evolutionary biologists.58
No matter how much the concept of the molecular clock
is given an extraordinary scientific and technical gloss, it is still,
as Denton has made clear, the product of circular reasoning and actually
explains nothing. That is because in order to construct a molecular
clock, one must first accept the claim that living things descended
from a common ancestor. Evolutionists first construct molecular clocks
on the basis of their preconception, and then use them, just as the
NAS authors do, as proof of descent from a common ancestor. Phillip
Johnson describes how evolutionists seek to impress people with this
theory, which may look very scientific, but is in reality an empty
shell:
Darwinists regularly
cite the molecular clock findings as the decisive proof that "evolution
is a fact." The clock is just the kind of thing that intimidates non-scientists:
it is forbiddingly technical, it seems to work like magic, and it
gives impressively precise numerical figures. It comes from a new
branch of science unknown to Darwin, or even to the founders of the
neo-Darwinian synthesis, and the scientists say that it confirms independently
what they have been telling us all along. The show of high-tech precision
distracts attention from the fact that the molecular clock hypothesis
assumes the validity of the common ancestry thesis which it is supposed
to confirm.59
As Johnson makes clear, the complex-appearing calculations
that so impress people cause them to believe that the molecular clock
is a scientific hypothesis that actually illuminates extraordinary truths.
The fact is, however, as we have already seen, that the concept of the
molecular clock employs circular reasoning, and is incapable of providing
any evidence for the theory of evolution. The NAS authors continue this
"maybe-they'll-believe-it" logic throughout the chapter in question,
setting out their so-called proofs one after the other.
The Purported Evolutionary Relationship Between
Whales And Hippopotamuses
At
the end of the chapter "New Proofs from Molecular Biology," a claim
is made that flies in the face of the scientific facts. The NAS claims
that comparisons of certain milk protein genes show that the ancestor
of the whale is the hippopotamus, and that this claim is also supported
by the fossil record. The truth, however, is that the scientists who
actually carried out this research, as well as experts on the origin
of whales, do not share the views of the NAS. Scientists at the Tokyo
Institute of Technology who carried out the research, which was published
in the August 14, 1997, issue of Nature, wrote at the end of their article
that the hippopotamus origin of the whale is incompatible with both
the fossil record and morphological comparisons:
The conclusions
from our retropositional analysis are inconsistent with earlier morphologically
based hypotheses. Paleontological and morphological data suggest
that modern whales originated from the Archaeocetes (primitive aquatic
cetaceans), which first appeared in the early Eocene epoch. The Archaeocetes
are believed to have originated from mesonychians [a family of odd-toed
ungulates], which appeared before the Eocene. However, the most primitive
artiodactyls [even-toed ungulates] (Dichobunids) first appeared in
the early Eocene, and the origin of nearly all the families of artiodactyls
can only be traced back to the middle or the late Eocene. Such
a sequence of appearance of these animals is inconsistent with our
molecular data... We believe that recent molecular data will
lead to the reinterpretation by palaeontologists of many fossil records
of Artiodactyla to match our conclusions. Extensive morphological
reversals and convergences, as well as large gaps in the fossil record,
will then have to be acknowledged.60
Michel C. Milinkovitch, of the Molecular Biology Department
of the University of Brussels, and J.G.M. Thewissen of Northeastern
Ohio Medical School, wrote in the same issue of Nature that the Japanese
scientists' findings on the origin of the whale conflicted with both
morphological and paleontological data, contrary to the claims of
the NAS:
The molecular analyses of Shimamura
et al.3, reported on page 666 of this issue, further disrupt phylogenetic
dogma. Indeed, not only do the authors confirm the close relationship
between artiodactyls and cetaceans, but they propose that cetaceans
are deeply nested within the phylogenetic tree of the artiodactyls.
These results strikingly contradict the common
interpretation of the available morphological data (supporting artiodactyl
monophyly [common descent]) and, if correct, would make a cow
or a hippopotamus more closely related to a dolphin or a whale than
to a pig or a camel.61
Furthermore,
these scientists acknowledge that this matter is still subject to debate
saying:
But the issue is still controversial,
because the exact means by which molecular sequence data should be
analyzed remains debated.62
Analyses of other molecules have similarly
produced contradictory findings. The zoologist John Gatesy states
that analyses of sea mammals' blood coagulation protein have presented
an evolutionary link between whales and hippopotamuses, but that this
conflicts with the paleontological findings.63
As we have seen, the scientists who actually did the
research openly state that the molecular comparisons performed in
order to discover the origin of the whale conflict with morphological
and paleontological findings. The NAS, on the other hand, adopts the
opposite point of view, despite that fact that the truth of the matter
is well known. It is evident that this is not a question of lack of
knowledge, because the NAS claims to be one of the world's foremost
scientific institutions. It appears that the NAS is deliberately making
groundless claims to convince people with no knowledge of the subject,
who have no means of checking the veracity of what they read, or feel
no need to, that evolution is true.
We have already examined the invalidity of the evolutionist
theses on the subject of the origin of whales in our article "A
Whale Fantasy From National Geographic." (www.harunyahya.com/70national_geographic_sci29.html)
As we have explained there in some detail, the thesis that whales
evolved from terrestrial mammals is a tale devoid of any scientific
foundation. There are considerable morphological differences between
the oldest whales and such extinct land mammals as Pakicetus
and Ambulocetus, which are suggested as the whale's terrestrial
ancestors. On the other hand, the "adaptive processes" proposed by
evolutionists for "the evolution of the whale" constitute an unscientific
scenario based on Lamarckian reasoning.
Sea mammals possess exceedingly distinct features. To
claim that these creatures underwent the dozens of different adaptations
necessary for the transition from land to sea as the result of morphological
deformities brought about by random mutations is itself a major problem
for the theory of evolution. The theory is quite unable to explain
how such a transition might have come about. In 1982, the evolutionist
science writer Francis Hitching said this on the subject:
The problem for Darwinians is in trying
to find an explanation for the immense number of adaptations and mutations
needed to change a small and primitive earthbound mammal, living alongside
and dominated by dinosaurs, into a huge animal with a body uniquely
shaped so as to be able to swim deep in the oceans, a vast environment
previously unknown to mammals . . . all this had to evolve in at most
five to ten million years-about the same time as the relatively trivial
evolution of the first upright walking apes into ourselves.64
Any creature which is suggested as having undergone such
a transition would be disadvantaged both in the sea and on land during
that process and would be eliminated. The NAS's claims regarding the
origin of marine mammals and molecular comparisons are totally based
on speculation, and are far from being scientific and rational.
Conclusion
Molecular biology offers no evidence to support the theory
of evolution's claim that all the different living categories on earth
descended from a single common ancestor by means of random mutations
and natural selection. The gradual divergence expected by the theory
appears nowhere in the fossil record or molecular analyses.
Michael Denton makes the following comment based on the
findings in the field of molecular biology:
Each class at a molecular level is unique, isolated
and unlinked by intermediates. Thus molecules, like fossils, have
failed to provide the elusive intermediates so long sought by evolutionary
biology… At molecular level, no organism is
"ancestral" or "primitive" or "advanced" compared with its relatives…
There is little doubt that if this molecular evidence had been available
one century ago… the idea of organic evolution might never have been
accepted. 65
THE NAS'S CONFESSIONS
Even
though the NAS blindly defends the theory of evolution in its booklet
Science and Creationism and suggests that there is definitive
evidence for the theory in all fields, it has also admitted in its publication
Proceedings of the National Academy of Sciences (PNAS) that
the theory contains a number of contradictions. An essay entitled "The
New Animal Phylogeny: Reliability and Implications," published in the
April 25, 2000 issue of PNAS, is just one of many articles full of such
confessions.
Another essay, prepared by scientists from France's Centre
National de la Recherche Scientifique (CNRS), details how unreliable
and contradictory evolutionary family trees are, and expresses the
need for new theories to be produced. The following statements appear
in the article:
DNA sequence analysis dictates new interpretation
of phylogenic trees. Taxa that were once thought to represent successive
grades of complexity at the base of the metazoan tree are being displaced
to much higher positions inside the tree. This leaves no evolutionary
"intermediates" and forces us to rethink the genesis of bilaterian
complexity.
Worst of all, contradictory trees have
kept pouring in, often with insufficient critical assessment.
Such a rapid splitting of lineages appears
to have occurred repeatedly during evolution, and it renders reconstruction
of the order of splits very difficult even with large amounts of sequence
data.
The new molecular based phylogeny has
several important implications. Foremost among them is the disappearance
of "intermediate" taxa between sponges, cnidarians, ctenophores, and
the last common ancestor of bilaterians or "Urbilateria."
...A corollary is that we have a major gap in the stem
leading to the Urbilataria. We have lost the hope, so common in older
evolutionary reasoning, of reconstructing the morphology of the "coelomate
ancestor" through a scenario involving successive grades of increasing
complexity based on the anatomy of extant "primitive" lineages.1
1- "The New Animal
Phylogeny: Reliability and Implications," Proceedings of National
Academy of Sciences, April 25, 2000, vol. 97, no: 9, pp. 4453-4456.
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